Selected publications on exercise, physical activity and multiple sclerosis
Scholarly output is an important part of our work. Click the links below to read our research, which covers a wide range of topics such as the effects of exercise on multiple sclerosis symptom management, neurological mechanisms of exercise, and the relationship between physical activity and brain health.
Publications Heading link
Zheng P, DuBose NG, DeJonge SR, Jeng B, Hibner BA, Motl RW. Vascular function in multiple sclerosis: Systematic review with meta-analysis. Mult Scler Relat Disord. 2024 Nov;91:105902. doi: 10.1016/j.msard.2024.105902. Epub 2024 Sep 22. PMID: 39342812.
Zheng P, Phillips SA, Duffecy J, DeJonge SR, DuBose NG, Motl RW. Remotely-delivered exercise training program for improving physical and cognitive functions among older adults with multiple sclerosis: Protocol for an NIH stage-I randomized controlled trial. Contemp Clin Trials. 2024 Sep;144:107636. doi: 10.1016/j.cct.2024.107636. Epub 2024 Jul 20. PMID: 39038700.
Huynh TLT, Neal WN, Barstow EA, Motl RW. Preferred Behavior Change Techniques for Physical Activity Interventions among Persons Newly Diagnosed with Multiple Sclerosis: A Qualitative Study. Behav Med. 2024 Jun 7:1-11. doi: 10.1080/08964289.2024.2355131. Epub ahead of print. PMID: 38848105.
DeJonge SR, DuBose NG, Motl RW, Baynard T, Fernhall B. Inverse association between arterial stiffness and perceived fatigue independent of disability status and BMI in multiple sclerosis. Neurol Sci. 2024 Oct;45(10):4957-4962. doi: 10.1007/s10072-024-07556-y. Epub 2024 May 7. PMID: 38713451.
Motl RW, Bombardier CH, Duffecy J, Hibner B, Wathen A, Carrithers M, Cutter G. Study protocol: exercise training for treating major depressive disorder in multiple sclerosis. BMC Neurol. 2024 Apr 17;24(1):131. doi: 10.1186/s12883-024-03634-y. PMID: 38632556; PMCID: PMC11022372.
Motl RW, Sandroff BM, Benedict RHB, Aldunate R, Cutter G, Barron E. Internet-delivered lifestyle physical activity intervention for cognitive processing speed in multiple sclerosis. Contemp Clin Trials. 2024 Mar;138:107446. doi: 10.1016/j.cct.2024.107446. Epub 2024 Jan 17. PMID: 38242351; PMCID: PMC11162540.
Huynh TLT, Williams MJ, Motl RW. Walking and physical performance in black and white adults with multiple sclerosis controlling for social determinants of health. Mult Scler Relat Disord. 2024 Mar;83:105439. doi: 10.1016/j.msard.2024.105439. Epub 2024 Jan 9. PMID: 38219300.
Zheng P, Sandroff BM, Motl RW. Free-living ambulatory physical activity and cognitive function in multiple sclerosis: the significance of step rate vs. step volume. J Neurol. 2024 Apr;271(4):1638-1648. doi: 10.1007/s00415-023-12169-0. Epub 2024 Jan 12. PMID: 38214757.
Zheng P, Jeng B, Huynh TLT, Aguiar EJ, Motl RW. Free-Living Peak Cadence in Multiple Sclerosis: A New Measure of Real-World Walking? Neurorehabil Neural Repair. 2023 Oct;37(10):716-726. doi: 10.1177/15459683231206741. Epub 2023 Oct 21. PMID: 37864454.
DuBose NG, DeJonge SR, Jeng B, Motl RW. Vascular dysfunction in multiple sclerosis: Scoping review of current evidence for informing future research directions. Mult Scler Relat Disord. 2023 Oct;78:104936. doi: 10.1016/j.msard.2023.104936. Epub 2023 Aug 9. PMID: 37619375.
Motl RW, Kidwell-Chandler A, Sandroff BM, Pilutti LA, Cutter GR, Aldunate R, Bollaert RE. Randomized controlled trial of the behavioral intervention for physical activity in multiple sclerosis project: Social cognitive theory variables as mediators. Mult Scler Relat Disord. 2023 Oct;78:104933. doi: 10.1016/j.msard.2023.104933. Epub 2023 Aug 9. PMID: 37586313.
Jeng B, DuBose NG, Martin TB, Šilić P, Flores VA, Zheng P, Motl RW. Updated Systematic Review and Quantitative Synthesis of Physical Activity Levels in Multiple Sclerosis. Am J Phys Med Rehabil. 2024 Apr 1;103(4):284-292. doi: 10.1097/PHM.0000000000002312. Epub 2023 Oct 5. PMID: 37408136.
Jones CD, Kidwell-Chandler A, Cederberg KL, Sikes EM, Motl RW. Do fatigue and depression have a bivariate association with device-measured physical activity behavior in persons with multiple sclerosis? Disabil Rehabil. 2024 Jun;46(12):2522-2527. doi: 10.1080/09638288.2023.2225876. Epub 2023 Jun 22. PMID: 37350026.
Flores VA, Šilić P, DuBose NG, Zheng P, Jeng B, Motl RW. Effects of aerobic, resistance, and combined exercise training on health-related quality of life in multiple sclerosis: Systematic review and meta-analysis. Mult Scler Relat Disord. 2023 Jul;75:104746. doi: 10.1016/j.msard.2023.104746. Epub 2023 May 1. PMID: 37172366.
Huynh TLT, Silveira SL, Motl RW. Physical Activity and Quality of Life in Persons Newly Diagnosed With Multiple Sclerosis: A Cross-sectional Study. Arch Phys Med Rehabil. 2023 Nov;104(11):1820-1826. doi: 10.1016/j.apmr.2023.04.004. Epub 2023 Apr 28. PMID: 37119953.
Šilić P, Motl RW, Duffecy J. Multiple sclerosis and anxiety: Is there an untapped opportunity for exercise? Mult Scler Relat Disord. 2023 May;73:104698. doi: 10.1016/j.msard.2023.104698. Epub 2023 Apr 3. PMID: 37058904.
Motl RW, Kidwell-Chandler A, Sandroff BM, Pilutti LA, Cutter GR, Aldunate R, Bollaert RE. Primary results of a phase-III, randomized controlled trial of the Behavioral Intervention for increasing Physical Activity in Multiple Sclerosis project. Mult Scler. 2023 Mar;29(3):415-426. doi: 10.1177/13524585221146430. PMID: 36843446.
Motl RW, Kinnett-Hopkins D, Neal W, Flores E, Pekmezi D, Flores V. Targeted exercise for African-Americans with multiple sclerosis: Project TEAAMS. Contemp Clin Trials. 2023 Mar;126:107088. doi: 10.1016/j.cct.2023.107088. Epub 2023 Jan 18. PMID: 36669728.
Zheng P, Pilutti LA, DuBose NG, Motl RW. Vascular function and cognition in persons with multiple sclerosis: Preliminary examination. Mult Scler Relat Disord. 2023 Feb 15;71:104578. doi: 10.1016/j.msard.2023.104578. Epub ahead of print. PMID: 36805173.
Motl RW, Fernhall B, McCully KK, Ng A, Plow M, Pilutti LA, Sandroff BM, Zackowski KM. Lessons learned from clinical trials of exercise and physical activity in people with MS – guidance for improving the quality of future research. Mult Scler Relat Disord. 2022 Dec;68:104088. doi: 10.1016/j.msard.2022.104088. Epub 2022 Aug 5. PMID: 35987111.
Jeng B, Motl RW. No association between body composition and walking outcomes in multiple sclerosis. Mult Scler Relat Disord. 2022 Dec;68:104242. doi: 10.1016/j.msard.2022.104242. Epub 2022 Oct 17. PMID: 36274282.
Silveira SL, Motl RW, Marquez DX, Salter A. Rates and patterns of physical activity among Hispanics with multiple sclerosis in the NARCOMS Registry. Mult Scler Relat Disord. 2022 Sep;65:104018. doi: 10.1016/j.msard.2022.104018. Epub 2022 Jul 2. PMID: 35810721.
Jeng B, Šilić P, Huynh TLT, Motl RW. Sedentary behavior and lower-extremity physical function across the lifespan of adults with multiple sclerosis. Int J Environ Res Public Health. 2022 Sep 30;19(19):12466. doi: 10.3390/ijerph191912466. PMID: 36231766; PMCID: PMC9566509.
Sasaki JE, Bertochi GFA, Meneguci J, Motl RW. Pedometers and Accelerometers in Multiple Sclerosis: Current and New Applications. Int J Environ Res Public Health. 2022 Sep 19;19(18):11839. doi: 10.3390/ijerph191811839. PMID: 36142112; PMCID: PMC9517119.
Huynh T, Jeng B, Motl RW. Physical activity and vascular comorbidity in Black and White persons with multiple sclerosis: A cross-sectional study. Disabil Health J. 2022 Jul;15(3):101314. doi: 10.1016/j.dhjo.2022.101314. Epub 2022 Mar 8. PMID: 35365422; PMCID: PMC9308665.
Motl RW, Sandroff BM. Physical exercise in multiple sclerosis is not just a symptomatic therapy: It has a disease-modifying effect-Yes. Mult Scler. 2022 May;28(6):859-861. doi: 10.1177/13524585211061651. Epub 2022 Mar 16. PMID: 35293819.
Jones CD, Jeng B, Silic P, Motl RW. Do device-measured physical activity and sedentary behavior differ by depression symptom status in persons with multiple sclerosis? Mult Scler Relat Disord. 2022 Jul;63:103889. doi: 10.1016/j.msard.2022.103889. Epub 2022 May 14. PMID: 35636270.
Silveira SL, Jeng B, Cutter G, Motl RW. Perceptions of physical activity guidelines among wheelchair users with multiple sclerosis. Mult Scler J Exp Transl Clin. 2022 May 25;8(2):20552173221097580. doi: 10.1177/20552173221097580. PMID: 35634012; PMCID: PMC9136460.
Sandroff BM, Motl RW, Yong VW, Cutter GR, Giovannoni G. Exercise training in multiple sclerosis. Lancet Neurol. 2022 Apr;21(4):313. doi: 10.1016/S1474-4422(22)00045-X. PMID: 35305335.